A New Reaction of Tris(alkylthio)cyclopropenium Salt withm-Substituted Anilines Affording Quinoline Derivatives
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چکیده
منابع مشابه
Synthesis and biological activities of new substituted thiazoline-quinoline derivatives.
5-Acyl-8-hydroxyquinoline-2-(3'-substituted-4'-aryl-2,3-dihydrothiazol-2'-ylidene)hydrazones, 5a-e to 10a-c, were prepared by the reaction of appropriate 5-acyl-8-hydroxyquinoline-4-substituted thiosemicarbazones 3a-e and phenacyl bromides 4a-e. Structures of the new compounds were verified on the basis of spectral and elemental analyses. Twenty-eight new compounds were tested for their possibl...
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Background: In this study, we evaluated antibacterial and antifungle activity of these derivatives against gram positive (Staphylococcus aureus, Bacillus subtilis, B. cereus), gram negative (Proteus vulgaris) bacteria and fungale (Candida albicans, C. tropicalis and C. glabrata). Methods: The broth macro dilution and well agar diffusion methods were used for determination of inhibition zoom (I...
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Readily available triethylammonium 1-(2-oxoindolin-3-ylidene)-2-aroylethanethiolates are efficiently converted into a variety of fully substituted thiophene derivatives by copper(I)-catalyzed denitrogenative reactions with terminal alkynes and N-sulfonyl azides. This new reaction simultaneously installs C-N, C-S, and C-C bonds, allowing direct formation of highly functionalized thiophenes with ...
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A novel method for the synthesis of pyrazolo[1,5-a]quinolines under the transition-metal-free conditions has been developed. This method involves a novel combination of aromatic nucleophilic substitution and Knoevenagel condensation reactions to give pyrazolo[1,5-a]quinolines.
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ژورنال
عنوان ژورنال: Bulletin of the Chemical Society of Japan
سال: 1988
ISSN: 0009-2673,1348-0634
DOI: 10.1246/bcsj.61.1793